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Currently, two New Drug Applications (NDAs) for mazdutide are under review by Chinas NMPA: Chronic weight management in adults with overweight or obesity Glycemic control in adults with type 2 diabetes Mazdutide is being evaluated across six phase 3 studies under the GLORY and DREAMS series: GLORY-2: Moderate-to-severe obesity GLORY-3: Obesity with metabolic dysfunction-associated fatty liver disease (MAFLD) DREAMS-1/2/3: Various cohorts of type 2 diabetes patients Future trials are planned in adolescents, sleep apnea, MASH, and heart failure with preserved ejection fraction (HFpEF)

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If the conflict drags on or the Strait of Hormuz stays blocked, reserves may need to be released more slowly, he said