There are several factors that can make you more likely to develop a mouth ulcer, including: stress, anxiety or hormonal changes injury or damage to your mouth, such as from dentures or braces reaction to certain foods, such as chocolate, peanuts or coffee some diseases, such as coeliac disease some medicines and medical treatments having an iron deficiency or vitamin B deficiency viruses, such as human papillomavirus (HPV) About 4 in every 10 people who get mouth ulcers have a family member who also gets them
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Most guidelines suggest screening every 10 years for average-risk individuals, but high-risk patients may need more frequent exams