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In fact, the number of chromosomal aberrations in the resveratrol group was like mice who were not irradiated at all

Pretreatment with L-NNA (20 mg/kg i.p.) prior to PTX (10 mg/kg i.p.) produced a small but significant decrease in SOD activity, as compared to PTX-alone and addition of L-arginine (50 mg/kg i.g.) to L-NNA (20 mg/kg i.p.), prior to intraperitoneal PTX application, resulted in the increment of SOD activity similar to that observed in the PTX-treated rats without L-NNA pretreatment ( Fig

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The absence of clinical trials means long-term effects, drug interactions, and organ-specific toxicity remain unknown

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