The Journal of Investigative Dermatology, 143 (9), 1700-1707
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First, the regulatory network of ferroptosis is extremely complex, involving interactions among iron metabolism, lipid chemistry, ROS generation and scavenging systems, and multiple signaling pathways
Thus, insulin resistance leading to elevated portal insulin levels may explain, at least partially, the overlap in individual IGF-I levels between older GH-deficient subjects and GH-sufficient subjects (85, 86)
The elastic net and parameters were tuned using grid search to minimize tenfold crossvalidated average precision
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