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This was due to increased plasma glycerol levels (which is an indicator of lipolysis) and in vivo fat oxidation

Thus, it demonstrates efficient clearance and limited systemic accumulation

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Several technical reasons may explain our distinctive findings, including differences in the microbiome sampling site, the limited n per group, singly housing mice, or the use of highly similar lean, Western, and high-fat diets which systematically exchanged fat content with carbohydrate content