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30 days (reconstituted) Mechanism Classification Primary Mechanism: NNMT (Nicotinamide N-methyltransferase) Inhibitor Target Enzyme: Nicotinamide N-methyltransferase Cellular Effect: Increases intracellular NAD+ and SAM levels Metabolic Pathway: NAD+ salvage pathway modulation Selectivity: Highly selective for NNMT (no cross-reactivity with related enzymes) Pharmacological Properties Route of Administration: Subcutaneous injection Bioavailability: High (subcutaneous)

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BPC-157: microvascular stabilization + inflammation modulation

Reference: Sikiric et al., 2010 Nitric oxide system involvement in BPC 157 effects PubMed: 2

FIG 14A-D Effect of the HGF antagonist Hinge on HGF- and Dihexa-mediated enhancement of mEPSCs in dissociated hippocampal neurons

SALT score dropped from 40% to 7.5%