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Zepbound, DailyMed (2025) Wegovy, DailyMed (2024) Lillys Zepbound (tirzepatide) superior to Wegovy (semaglutide) in head-to-head trial showing an average weight loss of 20.2% vs
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When lifestyle modifications alone prove insufficient, adding pharmacological tools can break through plateaus and create momentum for sustainable change
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The article frames this as the central tension: the drug suppresses the drive to eat at exactly the point where eating enough matters most for holding onto muscle