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Activated protein C however has not been explored for its protection over BBB integrity in the context of MS, but rather for its anti coagulation effects, reducing disease severity in MS models [128]

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Spirulina' s bioactive compounds, such as phycocyanin, may be responsible for the anti-inflammatory effects which are linked to mechanisms such as inhibiting the Nuclear Factor-B (NF-B) pathway, which is a key regulator of inflammation [20]

Among the 17 participants in the present study, the average power at both the LT (164.6W) and the IAT (215.6W), falls between the average power in the CME trial (129.4W) and the CVE trial (224.4W)