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DMSO 54.3%, p = 0.003) (Fig

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Selective serotonin reuptake inhibitors (SSRIs) : Antidepressants such as fluoxetine or sertraline may help reduce binge frequency, particularly when depression or anxiety co-exists, though they are used off-licence for this indication

In practical terms, this translates to an additional 34 kg weight loss compared to placebo

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Neither of these models had any relevant differences in terms of exposure compared with the presented model