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Description

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2004 May;134(5):1145-51

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The STEP-HFpEF trial with GLP-1 RAs semaglutide on HFpEF and obese patients demonstrated enhanced exercise capacity (7.9-point increase in KCCQ-CSS compared to placebo over 52 weeks) but lacked sufficient evidence on cardiovascular endpoints [9,11,12]

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The GLP-1 drug class includes Ozempic and Mounjaro, which are prescribed to treat diabetes, and Wegovy made by Novo Nordisk, which has been approved to treat weight loss

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