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Liposomal glutathione as a promising candidate for immunological rheumatoid arthritis therapy Weschawalit, S., et al

Boldly put, reduced glutathione is the active state of the molecule

The well-known NAC n-acetyl cysteine has a bioavailability of about 6% while NACET has a much higher bioavailability of 80%*

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For example, one clinical review noted that orally administered glutathione cannot be relied upon for therapeutic purposes, whereas IV or certain novel routes are needed for significant increases