Apart from inducing cFos activity in the same brain areas [696,726,730], LiCl and central GLP-1R agonism both decrease locomotor activity [668,731], slow GI motility and gastric emptying [573,732], reduce body temperature [732,733], and induce adverse gastrointestinal effects including nausea, emesis, and taste avoidance [696,[724], [725], [726],[734], [735], [736], [737]]
doi: 10.1016/S0140-6736(15)01024-7
doi: 10.1016/j.aoas.2016.07.003 92 KaurG.VikalY.KaurL.KaliaA.MittalA.KaurD.et al
demonstrated that erastin-induced ferroptosis elevated lysosome-associated membrane protein 2a (LAMP2a) expression and promoted chaperone-mediated autophagy (CMA) while facilitating GPX4 degradation, suggesting a possible connection between autophagy and ferroptosis (Wu et al., 2019)
Rotenone has also been shown to trigger mitophagy, induced by mild oxidative stress in a mitochondrial fission-dependent manner
Brown or amber discoloration indicates oxidation and degradation
