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Yakuchinone A attenuated the mRNA expression of IL-6, IL-8, and TNF- in the presence of TNF- on human epidermal keratinocytes (HaCaT cells)

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For instance, the HADS is often preferred in IBD research because it omits somatic criteriasuch as fatigue, sleep disturbances, and weight changesthat are inherently part of the IBD clinical picture (Vaughan et al., 2019)