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Hyperactivation of Drp1-mediated fission promotes mitophagy and survival, while its inhibition re-sensitizes CRC cells to apoptosis, positioning mitochondrial quality control as a viable metabolic checkpoint for combination therapy (244)

Its 3-letter sequence, Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Asn-His (31 residues as tabulated with N-terminal modification), features a single methionine that analysts should note as a potential oxidation site during method development, alongside multiple basic residues (Arg, Lys, His) that dominate its charge state envelope in positive-mode ESI-MS

Effects of peripheral CCK receptor blockade on food intake in rats

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