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In vivo 1H NMR spectroscopy of rat brain at 1 ms echo time

Clavero-Jimeno, A

Schoenenberger & Monnier, Progress in Neurobiology (1977) Foundational studies characterising DSIPs role in sleep modulation and associated neurochemical mechanisms

63 The hemolytic anemia associated with Class I variants is indistinguishable from the congenital nonspherocytic hemolytic syndromes related to glycolytic enzyme deficiencies

E1 is a TPP-dependent -ketoacid dehydrogenase, E2 is a dihydrolipoamide transacetylase that binds one or two lipoyl groups via covalent amide linkages to lysine residues, and E3 is an FAD-containing dihydrolipoamide dehydrogenase that re-oxidizes dihydrolipoamide using NAD +

Another study identified ENSA-K63la as a glycolysis-driven lactylation event that triggers the SRCSTAT3CCL2 pathway, promoting recruitment and immunosuppressive polarization of TAMs, limiting CD8 T-cell infiltration, and contributing to immune checkpoint blockade resistance