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Last Updated: June 2026

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a , HT1080 OE GFP-GPX4 WT and HT1080 OE GFP-GPX4 R152H were treated with 4 M RSL3, 30 g/ml cycloheximide, and 100 M a-Tocopherol for 0, 2, 4, or 6 hours before Western Blot analysis of GPX4 and GADPH

To detect cytosolic and mitochondrial ROS, the cells (5 10 5 ) that were seeded in 60-mm dishes with indicated treatments were prepared and stained with MitoSox (5 M

The accumulation of lipid droplets in hepatocytes leads to the release of pro-inflammatory cytokines such as tumour necrosis factor-alpha (TNF), interleukin-6 (IL-6) and interleukin-8 and the activation of inflammatory signaling pathways including nuclear factor-kappa B (NF-B) and Jun N-terminal kinase (JNK) [27]

About this article Cite this article Zhang, Q., Luo, Y., Peng, L