The study was limited to individuals living in Sweden with an interest to stop using snus, and the external validity beyond this cohort is uncertain
However, other studies may use ultrasound, sample liquid near the lung or require minor incisions to collect larger tissue samples
A respondent is classified to be likely undergoing depression if the PHQ-9 score 10 according to the PHQ-9 scoring guide [33] and some previously published studies [34, 35]
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Synthetic nicotine is also found in dissolvable products, which are sold in the form of sticks, lozenges, strips or nicotine gum