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Following the same search strategy and inclusion criteria as a previous meta-analysis 1,2 , we updated the literature search in 14 databases from the last search date, 1 January to 20 October 2025, and identified an additional 405 studies for eligibility screening

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Native Americans metabolize nicotine faster than other ethnic groups which leads to a higher level of dependence

A related technique called acupressure involves pressing certain points on your body when a craving hits

A randomized controlled trial of oral selegiline plus nicotine skin patch compared with placebo plus nicotine skin patch for smoking cessation

Shiki Magata, who has been living in isolation at a research facility on a solitary island, Souhei Saikawa, together with Moe Nishinosono who got caught up in the middle of the case, decide to solve the mystery that has originated from the past 15 years