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This means that prevalence rates are unclear in other world regions

www.aihw.gov.au/reports/alcohol/alcohol-drugs-young-people 3

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By 1979, the magnitude of the epidemiological, pathological, clinical, and experimental evidence had grown to the point that the Surgeon Generals Report concluded: Smoking is causally related to coronary heart disease in the common sense of that idea and for the purposes of preventive medicine. The Health Consequences of SmokingCardiovascular Disease: A Report of the Surgeon General

When uncertain, start lower it is easier to increase strength than to deal with too much nicotine