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Prolonged exposure resulted in a change in OSCC morphology from polygonal to elongated, a decrease in the levels of the epithelial marker Cytokeratin-13 and an increase of mesenchymal markers (N-cadherin and -Smooth Muscle Acton (SMA)), indicating an Epithelial-to-Mesemchymal Transition (EMT) phenotype [121]

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They also plan to study other biological effects resulting from DNA damage that are even more closely related to the onset of chronic disease

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Using this estimate, we predict that if the cigarette price is increased by 10%, the daily cigarette smoking prevalence among men would decrease from 30.7% to 29.9% and the number of male smokers would decline by around 270 thousand