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[142] Canada [edit] In late November 2015, Bill 44 was passed by the National Assembly, which regulates e-cigarettes as tobacco products in Quebec, Canada
This is achieved through the merging of the mitochondrial outer membrane and inner membrane mediated by GTPases Mfn1 and 2 (Mfn 1/2) and OPA1, respectively (Liu et al., 2020)
The regulatory focus is on reducing waste and preventing underage vaping, rather than eliminating all vaping devices
A 2022 meta-analysis of 61 studies reported high certainty that people using nicotine e-cigarettes had higher quit rates, compared to people randomized to using nicotine replacement therapy
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