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Besides, it was discussed that the visceral fat accumulation was related to several pro-inflammatory mediators that might induce not only hepatic steatosis, but also hepatic damage and subsequent liver fibrosis (59)
Furthermore, smoking significantly elevates the risk of de novo malignancies post-transplant, including extrahepatic cancers, which contribute to long-term morbidity and mortality [109,110,111]
Over time, fibrosis restricts blood flow and, in its severe form, can become cirrhosis, a condition of permanent damage
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