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Additional input from policy makers and other clinicians to improve the design of the registry for maximal benefit with minimal time and financial cost will be critical

The trial randomized 458 people who smoked daily and wanted to quit to receive either a nicotine-containing e-cigarette and placebo tablets, varenicline and an e-cigarette without nicotine, or a placebo tablet and a nicotine-free e-cigarette for 12 weeks

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