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Smoking intensity may contribute to the discrepancy, since peripheral blood T cell subsets were not found to be different in light (1019 pack years) to moderate smokers (2049 pack years) 71,72 , but a decrease, rather than an increase, in CD4/CD8 was observed in heavy smokers (50120 pack years) 72,73

(3) Nicotine withdrawal is the set of physical and psychological symptoms that occur when a person who smokes cigarettes suddenly stops using nicotine

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