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Most recent amount of cigarettes smoked daily before onset of the present illness, lung cancer cases and matched controls with other diseases, Great Britain, 1948-1952

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Key parameters include the lung clearance index (LCI), Scond, Sacin, and functional residual capacity (FRC), which respectively reflect overall ventilation heterogeneity, convection-dependent heterogeneity in the conducting airways, diffusion-dependent heterogeneity in the peripheral airways and alveolar regions, and theresting end-expiratory lung volume (91)