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Along with inflammation, epithelial to mesenchymal transition have been reported in people who smoke and patients with COPD, which may be one of the shared mechanisms leading to lung cancer in these patients [87,88,89,90,91]

Ocala Star-Banner April 11, 1989: 7C

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Here, we performed an oral microbiome study of healthy and oral cancer patients to decipher the microbial dysbiosis due to the consumption of smokeless-tobacco-based products and also revealed the tobacco-associated microbiome

[37] Effect on youth [edit] Debate exists over whether players should be banned from using tobacco products during the games