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Among important toxic compounds identified, other than nicotine, are carcinogenic nitrosamines, derived from nitrites, amines, proteins and alkaloids present in the leaf, polycyclic aromatic hydrocarbons resulting from the curing process, radioactive elements absorbed from the soil and the air, and cadmium in tobacco grown on cadmium-rich soils

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(1) Alphonse Mucha, Job, 1896

Factors such as rising temperatures, irregular rainfall, droughts, and floods in major tobacco-growing regions are increasingly impacting crop yields, leaf quality, and curing processes, resulting in an inconsistent supply of raw materials

Stroke A stroke occurs when a blood clot blocks an artery supplying blood to the brain