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Exposure to nicotine among youth is particularly dangerous since it affects key brain receptors, making young people more susceptible to nicotine addiction

The AAFP has recommended these as oral substitutes since 2000 [4]

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To check for heterogeneity, Q statistics and Higgins I 2 value was used

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For instance, tongue and mouth movement, including tongue sucking rawness and soreness of the tongue biting or chewing of the tongue, lips, or inner cheeks teeth clenching or grinding, known as bruxism Scientists are also beginning to recognize less common mouth and tongue effects of stimulant ADHD medications