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Collectively, these results suggest that PI3K/AKT signaling pathway activation may be involved in the pathogenesis of CS-induced pulmonary EMT and has potential therapeutic significance in COPD, lung cancer, and other smoking-related diseases

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Label salience was significantly higher in Canada than Mexico when considering the frequency of noticing warning labels and for the two depth-of-processing variables, which focused on the label making participants think about the dangers of smoking and about quitting smoking (Figure 2)