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Propylene glycol is approved and used as a vehicle for topical, oral, and some intravenous pharmaceutical preparations in the U.S

No throat-tax and unlimited joy, says the Boston of today

Each of these components of e-cigarette vapour has been demonstrated to pose a risk to the cardiovascular system: a) nicotine can increase blood pressure and heart rate, or cause inflammation or stiffness in the arteries

Thus, the first EC later became known as a cig-alike (Figure 2)

Scientific reports, 7(1), 1690

66 One recent study showed that hypertensive people who smoked less than 20 pack-years (one pack-year is defined as 20 cigarettes smoked every day for one year) had a 19% increase in cardiovascular death compared with those who never smoked, and those who smoked more than 20 pack-years had a 33% increase in death risk from cardiovascular disease