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In contrast, the CEP shows the lowest metabolic activity and greatest resilience to metabolic perturbations, where its chondrocyte-like cells are likely to have lower energy demands

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16 , compared with non-smokers, asymptomatic smokers have increased eosinophils in the airway mucosa, and there is a correlation between the number of eosinophils and epithelial integrity in smokers

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While lower solid-fuel use per person may help to reduce these health impacts, the overall reduction in health impacts may be limited by the effects of a growing and ageing population