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Competition from Sumatra later in the century inspired growers hereabouts to turn over a new leaf, so to speak, in tobacco growing

Acta Pharmacol Sin

ISSN 1744-8603

The Southern colonies, such as Virginia and the Carolinas, thrived economically through agriculture, particularly the cultivation of cash crops like tobacco and rice

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You will see another with a good pipe, laden with good tobacco, well lit, blowing incessantly down the mouth-piece and the stem until the moisture introduced with his breath into the bowl of his pipe effectually prevents the tobacco from burning, and puts out the fire