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Wen et al

Neural systems of reinforcement for drug addiction: from actions to habits to compulsion

Population-based surveys, used for monitoring and surveillance of health indicators such as smoking prevalence, are typically large enough to provide national and state trends but do not have the necessary power to generate detailed risk profiles at a sub-national level 10

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[Note 3] What this tells us is that even when a molecule fulfills all the conditions (cyclic, conjugated, flat, 4 pi electrons), the symmetric geometry is particularly unstable