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No date on my copies though I would guess the late 1950s or early 1960s

As a result, more patients will be able to start and stay on clozapine without unnecessary disruptions, improving their stability and overall quality of life. Clozapine Plays an Important Role in Schizophrenia Treatment Clozapine is the only approved option for these treatment-resistant patients

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It is one of the healthiest towns in the State, and with proper facilities for speedy communication with other towns, might be the seat of a flourishing trade