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Smoking and the patency of lower extremity bypass grafts: a meta-analysis

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Approximately 46% of NNN and 26%-37% of NNK in tobacco is preformed and the remainder is pyrosynthesized from nicotine during smoking (36)

If you smoke, you increase your risk of at least 16 different types of cancer including lung, mouth (oral cavity), throat (pharynx), oesophagus, stomach, bowel, liver, pancreas, nasal cavity and sinuses, voice box (larynx), cervix, ovary, bladder, kidney, ureter and bone marrow (myeloid leukaemia)