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American Journal of Clinical Nutrition 83(5):1126-1134

Compared to those who have never smoked, men who smoke are 23 times more likely to develop lung cancer, while women are 13 times more likely to be diagnosed with this deadly disease

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This is consistent with studies from the European Union 26,27 , the United States 28 , and Chile 30 , which found higher rates of flavored tobacco use in females, and a study from the United States which shows a higher prevalence of flavored tobacco use in certain ethnic groups (African and Hispanic) 28

He went on to appear in their films Barton Fink (1991), The Big Lebowski (1998), O Brother, Where Art Thou