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We will work with them as they transition out of the tobacco category in the coming months. Stopping cigarette sales comes at a price

Gottlieb and other public health officials are trying to strike a balance between the use of e-cigarettes to help adult smokers quit combustible tobacco and not hooking a new generation on nicotine through e-cigarettes

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In vitro studies using lung cell lines, A549 and H1650, exposed to e-liquid extracts showed high sphere formation and self-renewal activity that were diminished with the knock-out of Sox2 , as increased expression of Sox2 increases sphere formation or self-renewal ability [26]