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Mohan et al., Caffeine as an Antioxidant: Inhibition of Lipid Peroxidation Induced by Reactive Oxygen Species, Biochemica et Biophysica Acta, June 13, 1996;1282(1):6370

Cigarette Filter Ventilation and its Relationship to Increasing Rates of Lung Adenocarcinoma

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Subjects received open-label induction therapy at a dose based on their body weight (40 kg and 30) or who were non-responders (did not achieve a decrease in the PCDAI of 15 from baseline for 2 consecutive visits at least 2 weeks apart) were allowed to dose-escalate (i.e., switch from blinded every other week dosing to blinded every week dosing)