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Key Takeaways: Cigarette smoke contains 7,000 chemical compounds, including around 250 harmful and 69 carcinogenic chemicals

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Rosalind had little choice but to apply for a new grant and got one from the US National Institutes of Health

Optimal Elasticity : The leaves are cured to maintain flexibility, reducing the risk of cracking or tearing during rolling

At first, we found that addition of an end-repair step to fill in 5 overhangs and detect base-editor-modified gDNA resulted in high background and detection of only a small fraction (20%) of previously validated off-target sites (Extended Data Fig