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Cigarette smoking was especially high among males, those aged 25-64 years, people who had less education, American Indians/Alaska Natives, Americans of multiple races, those who had serious psychological distress, those who were uninsured or insured through Medicaid, those living below the poverty level, those who had a disability, those who were lesbian, gay, or bisexual, and those who lived in the Midwest or South

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When NO donor was added to tobacco induced cells, development of partial cell deaths was observed which confirmed the role of NO as the cell death mediator Biomarkers Major nicotine metabolite Cotinine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) Essentiality and deficiency (specific to metals) : N/A References Engstrom P.F., Clapper, M.L and Schnol, R.A

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