Epidemiology Bimodal age distribution: 1530 yrs and 5070 yrs Slight male predominance Higher prevalence in urban populations Etiology & Pathogenesis Multifactorial: genetic predisposition + immune dysregulation + environmental triggers Inflammation limited to mucosa and submucosa Begins in the rectum extends proximally (continuous lesions) Clinical Features Intestinal: Bloody diarrhea Mucus in stool Tenesmus Urgency Abdominal pain (LLQ) Systemic: Fatigue Weight loss Fever (severe disease) Extra-intestinal Manifestations Musculoskeletal: Peripheral arthritis, sacroiliitis Skin: Erythema nodosum, pyoderma gangrenosum Eyes: Uveitis, episcleritis Hepatobiliary: Primary sclerosing cholangitis (PSC) Extent (Montreal classification simplified) Proctitis rectum only Left-sided colitis up to splenic flexure Pancolitis entire colon Diagnosis Colonoscopy with biopsy gold standard Continuous erythema, friability, ulceration Histology: Crypt abscesses, mucosal inflammation Labs: ESR/CRP, anemia Exclude infection (stool cultures, C
As Naylor is about to appear before a U.S
In this blog, we delve into the captivating world of the most expensive cigarette lighters of 2023
At six foot three, he is more than a foot taller than I am
17.49 Road Kill * 10.oz..chopped.steak.smothered.with.sauted.onions, sauted.mushrooms.and.jack.cheese
[32] In 2017, Remini co-starred in the comedy films Mad Families , The Clapper , and Handsome
