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Research highlights that smoking reduces immune function and causes inflammation in the body

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However, the culture and rituals surrounding pipe smoking often focus on the relaxation, flavor appreciation, and contemplative aspects of the experience rather than purely on nicotine intake

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While we anticipated that results for the subcortical VOIs would be similar to WB results (and to one another due to values being highly intercorrelated), we ran these analyses because there was a possibility of regional differences and the data could be useful for future research using similar methods