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Semin Respir Crit Care Med 26:265272 Ahrendt SA, Decker PA, Alawi EA, Zhu Yr YR, Sanchez-Cespedes M, Yang SC, Haasler GB, Kajdacsy-Balla A, Demeure MJ, Sidransky D (2001) Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung

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Others can go days or even weeks without smoking, but then experience a deep, sudden urge to do it

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Consistent with findings from the European Union 26,27 , the United States 28 , and Chile 30 , we also found that, in Singapore, current use of flavored cigarettes is correlated with being younger in age (2039 years), having initiated at a later age, and having a lower nicotine dependence level