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Tobacco smoke in itself is a very dangerous form of air pollution

In light of the opioid epidemic, its worth examining the relationship between vaping and opioid use to determine likely health outcomes for individuals with a polysubstance misuse habit

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Study Characteristics The 22 studies analyzed include seven cohort studies 19, 23, 39, 40, 43,44,45 and fifteen case-control studies 17, 18, 20,21,22, 24,25,26,27,28, 32, 37, 38, 41, 42 , with a total of 795,632 cases and 1,829,256 control participants

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Sex was categorized as male or female