Here, we use single-cell RNA-sequencing (scRNA-seq) to define the transcriptional cell types and states of the tracheal airway epithelium in smokers and non-smokers, infer the lineage relationships among these cells, and determine the influence of cigarette smoke on individual surface and SMG airway epithelial cell types with single-cell resolution
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Whether using it as a hand-to-mouth oral crutch or as a replacement feeding for those now absent nicotine induced adrenaline releases that once pumped stored fats and sugars into the blood with each new puff, the net effect is the same - extra body weight
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2-AG or AEA is then liberated into the synaptic cleft and interact with CB1 receptors in the presynaptic membrane
