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Indeed, individuals with genetic polymorphisms in CYP2D6 were more likely to have participated in more antidepressant medication trials and also have been shown to switch among antidepressants more often (176, 177)

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They are also useful for treating ulcers caused by Zollinger-Ellison syndrome

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These nerves are activated by a wide range of stimuli, including food extracts (capsaicin, wasabi, ginger, allicin, mustard oil), environmental irritants (vehicle exhaust, air pollution, tobacco smoke, burning vegetation), endogenous inflammatory mediators (prostaglandin E 2 , bradykinin), and acid (Mohammed et al., 1993