It was criticised for having a higher tar content than other brands and was probably more dangerous because consumers would be smoking more to extract the nicotine
(b) the use of ACASI, which helps reduce reporting bias
A Cochrane systematic review of the evidence concludes that there is high certainty evidence that vapes that contain nicotine increase long-term quit rates to a greater extent than Nicotine Replacement Therapy (NRT).[4] Furthermore, there is high certainty evidence that nicotine e-cigarettes, varenicline and cytisine are the stop-smoking aids most likely to help people quit smoking.[5] Varenicline and cytisine are only available on prescription and were used in less than 1% of quit attempts in 2022.[6] Vaping behaviour in never smokers About one in 70 adults who have never smoked currently vape (1.5%, Figure 5)
Although relatively safe when inhaled (67), GLY can also form thermal degradation products (68)
In fact, Japan's smoking rate is now among the lowest in the developed world." according to Roulet
High Blood Press Cardiovasc Prev 27, 349362 (2020)