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These effects occur because nicotine is a potent stimulant that impacts the central and peripheral nervous systems, altering heart rate, blood pressure, and neurotransmitter activity

FDAs 2012 draft guidance for Modified Risk Tobacco Products

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Nicotine gum is sugar-free, and the chewing motion actually stimulates saliva production

Studies show that a person with lung cancer who smokes and inhales nicotine is more likely to develop brain metastasis than a person who does not smoke

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