They may also help explain why former smokers display increased risk of depression and substance use ( Numerous studies indicate the beneficial effect of nicotine on cognition in pathological conditions, also associated with cognitive deficit such as Alzheimers disease, Parkinsons disease, schizophrenia, stress-induced anxiety, depression, and drug-induced memory impairment ( Such positive effects of nicotine and tobacco on neurocognition, mood, and other psychiatric symptoms constitute a mechanism that may contribute to the high coexistence of TUD and other mental disorders
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