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At high concentrations, ECA induced the recruitment of inflammatory cells such as neutrophils, oxidative stress and the upregulation of metalloproteinases such as MMP9 and MMP12 [13, 18, 28]

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210 Po is omnipresent in the rocks and soils that make up Earths crust, in the atmosphere, and in the ecosystem of waters as a result of the decay of 222 Rn and subsequent dry or wet deposition